Categorized | Prostate Health

Long Term Acetaminophen Use Associated with Lower Prostate Cancer Risk

A new study from American Cancer Society shows that acetaminophen use of 30 tablets a month or more for five or more years was associated with an estimated 38% lower risk for prostate cancer.  This study is one of the two studies of prostate cancer to date that have examined the association with acetaminophen use that was both long-term and regular.

Researchers of this study examined the association between acetaminophen use and prostate cancer incidence by obtaining information completed by 78,485 men from the Cancer Prevention Study II Nutrition Cohort in 1992 study enrollment questionnaires. It was updated using follow up questionnaires in 1997 and every two years thereafter. From 1992 to 2007, 8,092 prostate cancer cases were identified. Current regular use of acetaminophen, more than 30 pills a month for 5 years or more was associated with lower risk of overall prostate cancer.  Current regular use of less than 5 years duration was not associated with prostate cancer risk.

Led researcher Eric Jacobs, Ph.D., an epidemiologist from American Cancer Society said “Our findings do not justify use of acetaminophen to prevent prostate cancer still the results of this study could lead to further research on acetaminophen that might provide biological insights about the process of prostate cancer development and how this process could be slowed.

Acetaminophen, commonly used as pain-reliever is relatively safe when used at recommended doses but can cause acute liver failure in an overdose.

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